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The Human Mesenchymal Stem Cell Tri-lineage Induction and Differentiation Kit is specifically formulated by YOCON BIOTECH COMPANY to facilitate the precise induction and differentiation of human mesenchymal stem cells (MSCs) into their three primary lineages: bone (osteogenic), cartilage (chondrogenic), and fat (adipogenic). This kit is vital for verifying the multipotent capabilities of MSCs derived from various human sources, including umbilical cord and adipose tissue, and is compatible with both serum-free and serum-containing culture systems, as well as induced pluripotent stem cells (iPSCs). By enabling researchers to consistently assess MSC differentiation, the kit supports rigorous cell identification and accelerates the evaluation of their therapeutic potential in diverse biomedical applications.
Osteogenic Differentiation
Chondrogenic Differentiation
Adipogenic Differentiation
Comprehensive Tri-lineage Induction: Provides all necessary reagents for the efficient and specific differentiation of MSCs into osteogenic, chondrogenic, and adipogenic lineages.
Broad Compatibility: Optimized for MSCs derived from various human sources, including umbilical cord and adipose tissue, and adaptable to serum-free, serum-containing, or serum replacement culture systems, as well as iPSC-derived MSCs.
Proven Differentiation Efficiency: Demonstrated success in inducing clear phenotypic changes and functional markers characteristic of osteoblasts, chondrocytes, and adipocytes.
Ready-to-Use Components: Streamlines experimental workflows by providing pre-formulated media and supplements.
Accurate MSC Validation: Enables precise identification and functional validation of MSCs, which is critical for their safe and effective application in cell-based therapies.
Accelerated Research & Development: Provides a standardized and efficient method for evaluating MSC potential, significantly speeding up the discovery and development process in regenerative medicine.
Optimized for Diverse Applications: Its compatibility with various MSC sources and culture systems makes it a versatile tool for a wide range of research fields, from basic science to preclinical studies.
Supports High-Quality Therapeutic Development: By ensuring the proper characterization of MSCs, the kit contributes to the development of safer and more effective cell therapies.
Performance Demonstration
Differentiation Effect— Osteogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for osteogenic differentiation, calcium nodules can be observed after 14 days, with a calcium nodule coverage rate exceeding 90% at 21 days.
Differentiation Effect — Chondrogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for chondrogenic differentiation, visible blue staining with Alcian Blue can be observed approximately 20 days after induction of differentiation.
Differentiation Effect — Adipogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for adipogenic differentiation, preliminary observation of lipid droplet formation can be made on day 8, and staining reveals a significant number of lipid droplets by day 12.
The Human Mesenchymal Stem Cell Tri-lineage Induction and Differentiation Kit is specifically formulated by YOCON BIOTECH COMPANY to facilitate the precise induction and differentiation of human mesenchymal stem cells (MSCs) into their three primary lineages: bone (osteogenic), cartilage (chondrogenic), and fat (adipogenic). This kit is vital for verifying the multipotent capabilities of MSCs derived from various human sources, including umbilical cord and adipose tissue, and is compatible with both serum-free and serum-containing culture systems, as well as induced pluripotent stem cells (iPSCs). By enabling researchers to consistently assess MSC differentiation, the kit supports rigorous cell identification and accelerates the evaluation of their therapeutic potential in diverse biomedical applications.
Osteogenic Differentiation
Chondrogenic Differentiation
Adipogenic Differentiation
Comprehensive Tri-lineage Induction: Provides all necessary reagents for the efficient and specific differentiation of MSCs into osteogenic, chondrogenic, and adipogenic lineages.
Broad Compatibility: Optimized for MSCs derived from various human sources, including umbilical cord and adipose tissue, and adaptable to serum-free, serum-containing, or serum replacement culture systems, as well as iPSC-derived MSCs.
Proven Differentiation Efficiency: Demonstrated success in inducing clear phenotypic changes and functional markers characteristic of osteoblasts, chondrocytes, and adipocytes.
Ready-to-Use Components: Streamlines experimental workflows by providing pre-formulated media and supplements.
Accurate MSC Validation: Enables precise identification and functional validation of MSCs, which is critical for their safe and effective application in cell-based therapies.
Accelerated Research & Development: Provides a standardized and efficient method for evaluating MSC potential, significantly speeding up the discovery and development process in regenerative medicine.
Optimized for Diverse Applications: Its compatibility with various MSC sources and culture systems makes it a versatile tool for a wide range of research fields, from basic science to preclinical studies.
Supports High-Quality Therapeutic Development: By ensuring the proper characterization of MSCs, the kit contributes to the development of safer and more effective cell therapies.
Performance Demonstration
Differentiation Effect— Osteogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for osteogenic differentiation, calcium nodules can be observed after 14 days, with a calcium nodule coverage rate exceeding 90% at 21 days.
Differentiation Effect — Chondrogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for chondrogenic differentiation, visible blue staining with Alcian Blue can be observed approximately 20 days after induction of differentiation.
Differentiation Effect — Adipogenic Differentiation
Using Yocon Biotech's GMP-grade serum-free mesenchymal stem cell (MSC) medium (product codes NC0106+NC0106.S) to culture P5 generation MSCs for adipogenic differentiation, preliminary observation of lipid droplet formation can be made on day 8, and staining reveals a significant number of lipid droplets by day 12.
