Newly Upgraded Bagged Culture Media: Leading the New Trend of Closed Culture in the Cell Therapy Industry

With the rapid development of the cell therapy industry and the increasingly improved industry regulations, some treatment projects have started to be clearly priced, and cell therapy is gradually moving from a relatively vague zone toward standardization and regularization. In this process, safety has become the core concern of enterprises. Closed-cell culture solutions have become the preferred choice for more and more enterprises due to their advantage of significantly reducing the risk of contamination. Against this backdrop, bagged culture media have emerged as a new favorite in the field of cell culture, characterized by their full closure, safety, and efficiency.

Application Scenarios of Bagged Culture Media

Bagged culture media are widely used in biopharmaceuticals and cell therapy fields that require high cleanliness and closed operations, including:
● Bioreactor Culture: Suitable for large-scale cell expansion, such as the production of therapeutic products like CAR-T cells and stem cells.
● Antibody and Protein Production: In the preparation of biological products such as monoclonal antibodies and recombinant proteins, bagged culture media can reduce the risk of contamination and improve product consistency.
● Closed Cell Culture Systems: Compared with traditional open bottled culture media, bagged culture media are more suitable for automated, closed cell culture systems and comply with GMP requirements.

Core Advantages of Bagged Culture Media

● Fully Closed System to Eliminate Contamination: Compared with open bottled culture media, bagged culture media can minimize the introduction of external microorganisms and particulates, ensuring the safety of cell culture.
● Convenient Operation to Reduce Human Error: The pre-installed design reduces the steps of culture media preparation and transfer, minimizing operational risks and improving experimental efficiency.
● Strong Adaptability to Large-Scale Production: Supports seamless integration from small-scale laboratory to large-scale industrial production, meeting the needs of different stages.

Yocon Bagged Culture Media: Safe, Flexible, and Customizable

To meet the industry's demand for closed culture, Yocon Biotech has launched a new packaging format—bagged culture media, specially developed for the biopharmaceutical industry and designed for closed-cell culture in biopharmaceutical processes. The types of bagged culture media include a series of Youkang's core products such as serum-free media for stem cells and serum-free media for immune cells. Yocon Biotech ensures that raw materials, product assembly, and sterilization processes fully comply with cGMP and biopharmaceutical operational requirements.

●Complete Range of Specifications

A full range of product models is available, including different volumes of 50mL, 200mL, 1L, 2L, and 5L, meeting the needs of the entire process from R&D to production.

A wide variety of products are offered, including multiple serum-free culture reagents for stem cells and immune cells, with the flexibility to customize specific types according to customer needs.

●Excellent Physicochemical Properties and Biocompatibility

The bag film is a 7-layer composite membrane specially designed for biopharmaceuticals, with a thickness of 0.3mm. ULDPE is used as the liquid contact layer, which is compatible with various chemicals, has extremely low levels of extractables and leachables, contains no animal-derived components, and exhibits excellent physicochemical properties, biocompatibility, and barrier characteristics.

●Customized Production

Different pipelines and interfaces can be configured according to customer requirements.

Product Structure

Take the 5L bagged culture medium as an example:

Biocompatibility and Physicochemical Performance Verification

The membrane materials selected for Yocon Biotech's bagged culture media have undergone strict biocompatibility and physicochemical performance verification, including tests such as material purity evaluation, insoluble particle detection, in - vitro cytotoxicity tests, in - vivo biological response tests, in - vitro hemolytic performance tests, acid - and alkali - resistance tests, and evaluation of various extractables. All these tests comply with the requirements of relevant regulations such as the Chinese Pharmacopoeia, the United States Pharmacopeia, and the Administrative Measures for Packaging Materials and Containers in Direct Contact with Drugs.

Some Inspection Reports

Product Categories

Continuously updated (customizable according to customer requirements)